If You’re Tackling Your Cholesterol, Should You Do Weights or Cardio?

If You’re Tackling Your Cholesterol, Should You Do Weights or Cardio?

2026-01-11health
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Taylor
Good evening Project, I am Taylor, and this is Goose Pod, your personal deep dive into the stories that shape your world. It is Sunday, January 11th, at 11:00 PM, and we are closing out the weekend with a topic that is close to the heart, literally.
Holly
And I am Holly. It is so wonderful to be here with you tonight. We are exploring a question many of us face at the doctor's office. If you are looking to manage your cholesterol, should you reach for the heavy weights or head straight for the treadmill? It is a fascinating balance.
Taylor
It really is a strategic puzzle. Many people think it is an either-or situation, but the latest research suggests we should be looking at this like a corporate merger. You need both cardio and weight training because they actually target your cholesterol levels in very different, yet complementary, ways.
Holly
How absolutely lovely to think of our bodies as a collaborative system. According to Professor Neil Smart from the University of New England, each type of exercise acts on those blood fats with a unique touch. It is not just about moving, it is about the specific internal reactions we are triggering.
Taylor
The data is quite striking when you look at the numbers. On average, consistent exercise lowers the bad LDL cholesterol by about seven milligrams per deciliter. It also cuts down those artery-clogging triglycerides by eight milligrams. But the real headline is what it does for the good stuff, the HDL.
Holly
Yes, that little boost of two milligrams in HDL is more significant than it sounds. While drugs like statins are brilliant at bringing the bad numbers down, they often struggle to lift the good cholesterol up. Exercise fills that gap in a way that medicine and diet sometimes simply cannot manage alone.
Taylor
Exactly. Taylor here, thinking like a strategist, you want to maximize every asset. Cardio, like running or cycling, is your immediate fuel burner. It actually uses triglycerides in your bloodstream for energy. Over time, it reshapes your LDL particles, making them less dangerous and much easier for your body to clear out.
Holly
I found the description of those particles so charming. Apparently, cardio makes the LDL particles more puffy and less dense. When they are small and dense, they tend to settle into the artery walls, but when they are puffy, they just float along without causing nearly as much trouble.
Taylor
It is like the difference between a heavy pebble and a cotton ball. Then we have weight training, which is the protein-building powerhouse. Professor Smart theorizes that because HDL is a protein-rich cholesterol, it responds beautifully to resistance training, which involves breaking down and repairing muscle fibers. It is all about the repair.
Holly
The idea that lifting weights can increase our ability to remove bad cholesterol through a process called cholesterol efflux is just sophisticated simplicity at its best. By lifting at even moderate intensities, we are essentially helping our liver dispose of those clogging lipids much more efficiently than before.
Taylor
To see these results, you do not need to live in the gym. The benchmark is burning about one thousand to twelve hundred calories a week through exercise. That could be five fifty-minute walks or a few intense lifting sessions. It is about hitting that metabolic threshold to trigger the shift.
Holly
And the consistency is where the grace lies. Adding just one extra minute to a workout can lift your good cholesterol over a few months. It is such a gentle way to think about progress, knowing that every small addition to our routine is building a much healthier foundation for our future.
Holly
That is quite a significant difference in numbers. It can be a bit overwhelming for someone to choose the harder path of exercise when a pill seems so much more efficient. But we have to remember that medication alone often cannot improve the quality of our cholesterol in the same way.
Taylor
To really understand why this matters, we have to look at the history of how we have managed heart health. For decades, the narrative was almost entirely focused on diet. We were told to avoid eggs and butter, but we eventually realized that our internal chemistry is far more complex than that.
Holly
It truly is a journey of discovery. We used to view cholesterol as a simple villain, but now we see it as a complex delivery system. The liver is the central hub, and exercise acts like a supervisor, ensuring that the transport of these fats happens without any major traffic jams.
Taylor
That supervisor role is key. Think about enzymes like lipoprotein lipase. These are the workers in your blood that break down fats. When you engage in aerobic activity, you are essentially giving these enzymes a massive promotion. You are increasing their activity levels so they can clear the bad stuff faster.
Holly
How wonderful that we can empower our own internal enzymes. And it is not just about the moment of exercise. There is that concept from Mark Sarzynski about the other twenty-three hours of the day. Even if we work out for an hour, our metabolism is processing things all day long.
Taylor
That is the serious business strategist perspective. Your workout is the catalyst, but the metabolic benefits are the dividends that pay out while you are sleeping. Historically, we did not have the tools to see how exercise was reshaping LDL receptors in the cells, making them more receptive to clearing cholesterol.
Holly
It is so sophisticated how our bodies adapt. In the past, the focus was often just on weight loss, but now we understand that even if the scale does not move, the quality of our cholesterol is changing. Those puffy LDL particles we mentioned are a result of long-term cellular adaptation to movement.
Taylor
We also have to consider the role of inflammation. High cholesterol is dangerous because it damages the lining of blood vessels, but regular exercise creates an anti-inflammatory environment. It is like the body is producing its own internal medicine to keep the pipes clean and the system running at peak performance.
Holly
I love the idea of our bodies being their own pharmacy. It reminds me of the Mediterranean diet studies where researchers found that combining healthy fats with movement created a synergistic effect. It was never just about one thing, but a beautiful harmony of lifestyle choices working together for longevity.
Taylor
Right, and the evolution of sports medicine has brought us to this point where we can prescribe specific intensities. We used to just say go for a walk. Now, we can say that lifting at fifty to seventy-five percent of your max capacity is the sweet spot for boosting those HDL enzymes.
Holly
It makes the whole process feel so much more intentional. We are no longer just guessing; we have a roadmap. Knowing that three sessions of resistance training a week can target the big muscle groups and improve our lipid profile gives us such a clear and graceful path forward.
Taylor
And we cannot ignore the historical shift in how we view the good cholesterol, HDL. For a long time, we thought just having a high number was enough. But research now shows that the function of the HDL, its ability to actually carry away the bad fats, is what truly matters.
Holly
That is such an important distinction. It is not just about the quantity, but the quality and the purpose. Exercise improves the efficiency of that transport. It is like upgrading from a slow, old truck to a modern, high-speed delivery service that knows exactly where to take the waste.
Taylor
Exactly. We are moving away from the era of one-size-fits-all advice. We are understanding that the interplay between aerobic capacity and muscular strength is the ultimate strategy for vascular health. It is a comprehensive approach that looks at the body as an integrated, high-performing asset that needs maintenance.
Holly
It really is a testament to the wonder of human biology. By looking back at how far we have come from simple dietary restrictions to this complex understanding of cellular receptors and enzyme activation, we can truly appreciate the power we have to influence our own health every single day.
Taylor
Now, even with all this science, there is a massive tension between the quick fix of medication and the long-term commitment to lifestyle changes. Statins are incredibly potent. They can drop your total cholesterol by fifty percent, whereas diet and exercise might only manage a ten to twenty percent reduction.
Taylor
That is the strategic trade-off. You can take the pill to lower the numbers, but you cannot outrun a bad diet or a sedentary lifestyle. There is this dangerous trend in influencer culture where people think they can hack the system. Did you hear about that influencer who tried a ten-thousand-calorie daily challenge?
Holly
Oh, that was so heartbreaking and truly alarming. He was trying to prove a point for viral attention, but it led to heart failure. It is a tragic reminder that our bodies are not just for show or for experiments; they have real, biological limits that we must respect with grace.
Taylor
It highlights the dark side of the wellness industry. On one hand, you have medical science telling you to walk fifty minutes a day, and on the other, you have extreme influencers pushing unregulated strategies. The conflict arises when people lose trust in the steady, evidence-based methods because they want instant results.
Holly
It is so difficult to navigate all that noise. And even within the medical community, there is a debate about how much exercise is too much. Some worry about cardiac events during high-intensity workouts, especially for those who might have silent risks they are not even aware of yet.
Taylor
That is why the medical check-up is a non-negotiable part of the strategy. You cannot just jump into a high-intensity program if you have genetically high cholesterol. For those individuals, lifestyle changes might not be enough on their own to avoid medication, but they can definitely help lower the required dose.
Holly
I think that is a very sophisticated way to look at it. It is not an all-or-nothing battle between statins and the treadmill. They can be partners. The conflict shouldn't be about which one is better, but how to use them together to create the best possible outcome for the individual.
Taylor
Exactly. But the real obstacle for most people is time and adherence. Our modern world is designed for convenience, not for burning twelve hundred calories a week. There is a constant tension between our desk-bound jobs and the biological necessity of movement. It requires a total mindset shift to prioritize it.
Holly
It truly does. It is about reclaiming our agency. We often feel like victims of our schedules, but when we see exercise as a vital part of our self-care, it becomes a choice of empowerment. It is a way to lead ourselves toward a longer, more vibrant life, despite the obstacles.
Taylor
And there is the social pressure, too. For a long time, women were told to stay small and avoid heavy weights. There was this fear of getting bulky. That has created a historical gap in strength training for women, which we are only now starting to bridge as we realize its health benefits.
Holly
It is so lovely to see that shift happening. Women are embracing their strength and seeing their bodies as capable and powerful. Moving away from just aesthetics and toward performance and longevity is such a beautiful evolution in our culture. It is about being strong, not just looking a certain way.走向.
Taylor
The impact of this shift goes way beyond just cholesterol numbers. We are starting to understand that muscle is actually an endocrine organ. When you lift weights or run, your muscles secrete these bioactive substances called myokines. These little messengers have a massive impact on your entire cardiovascular system.
Holly
How absolutely fascinating! Myokines sound like a secret language our muscles use to talk to our hearts. They help create an anti-inflammatory environment and can even stimulate the regeneration of heart tissue. It makes the act of exercising feel so much more profound and holistic.
Taylor
It really changes the ROI on your workout. You are not just burning calories; you are investing in what we call muscle banking. By building strength and fitness now, you are creating a reserve of physical resilience that protects you against future illness and reduces overall mortality risk. It is pure strategy.
Holly
Muscle banking is such a wonderful term. It makes me think of every brisk walk as a deposit into a savings account for my future self. And it is not just for the individual. When more people are active, it has a beautiful ripple effect on public health and community well-being.
Taylor
The societal implications are huge. If we can reduce the prevalence of cardiovascular disease through these manageable lifestyle changes, we are looking at a much healthier, more productive population. We are seeing a move toward exercise is medicine as a standard part of clinical practice, which is a major win.
Holly
It is so encouraging to see doctors prescribing movement. And for women specifically, the shift toward strength training is a symbol of empowerment. Sculpted arms and strong legs are becoming signs of self-leadership and capability. It is about reclaiming our physical agency in a world that often tries to limit us.
Taylor
It is a cultural rebranding of health. We are moving away from the thin-at-all-costs era and into the era of metabolic health and functional strength. This has a direct impact on how we age, reducing the risk of muscle loss and keeping us independent and active much longer into our lives.
Holly
That longevity is such a gift. Being able to move with grace and ease as we get older is something we can start building right now. It is about the quality of the years we are living, ensuring they are full of vitality and the strength to enjoy everything life has to offer.
Taylor
And the best part is that it is accessible. You do not need a fancy gym to start walking or doing bodyweight exercises. The impact begins the moment you decide to move. That first walk starts burning those triglycerides immediately. The dividends start paying out from day one. It is a perfect entry point.
Holly
It really is. Such a simple, beautiful way to take care of ourselves. Knowing that our bodies are designed to respond so positively to movement gives me a sense of wide-eyed wonder. We have this incredible power within us to change our internal chemistry and our future health.
Taylor
Looking ahead, the future of cholesterol management is going to be incredibly personalized. We are moving toward personalized lipidology where AI and wearable tech will help us tailor our exercise prescriptions down to the minute. Imagine your watch telling you exactly how much resistance training you need today to optimize your HDL.
Holly
That sounds so sophisticated and helpful. To have a little guide on our wrist that understands our unique genetic makeup and our current needs would be absolutely lovely. It takes the guesswork out of being healthy and makes it feel much more like a gentle, guided journey.
Taylor
We are also seeing breakthroughs in pharmacogenomics, where tests can predict how your body will react to both statins and specific types of exercise. It is about finding the most efficient strategic roadmap for your unique biology. No more trial and error, just data-driven health decisions that save time and effort.
Holly
It is wonderful to think that medicine is becoming so much more personal and caring. The idea that we can use technology to support our natural biology is very exciting. It feels like we are entering a new age where we can truly harmonize our modern lives with our ancient physical needs.
Taylor
The next twenty years of exercise metabolism research are going to be a game-changer. We are just scratching the surface of how exercise reprograms our molecular pathways. Soon, we might have treatments that can mimic some of these effects for those who truly cannot exercise, ensuring everyone has a chance at heart health.
Holly
That is such a hopeful vision for the future. Ensuring that everyone has access to these benefits, regardless of their physical limitations, is truly graceful. It shows that our understanding of health is becoming more inclusive and more focused on the well-being of every single person. It is quite a beautiful prospect.
Taylor
It really is. The takeaway is clear: don't choose between the weights and the cardio. Integrate them. Use the cardio to clean the blood and the weights to build the machinery. Thank you for joining us on Goose Pod today, Project. It has been a pleasure diving into this with you.
Holly
It has been such a lovely evening. Remember that every small step you take is a gift to your heart. Thank you for listening to Goose Pod. We look forward to being with you again tomorrow. Have a peaceful night and stay strong.

To manage cholesterol effectively, combine weight training and cardio. Cardio uses triglycerides for energy and reshapes LDL, while weights build HDL-boosting muscle. This integrated approach, rather than an either-or choice, optimizes cardiovascular health by synergistically improving lipid profiles and promoting overall well-being.

If You’re Tackling Your Cholesterol, Should You Do Weights or Cardio?

Read original at Men's Health

SO YOUR DOCTOR said to include exercise in the lifestyle changes you’re making to get your cholesterol under control. But what kind of exercise, exactly, should you be doing?Both cardio and weight training affect your cholesterol in different ways. Ultimately, “you need both aerobic and resistance types as they complement each other," says Neil Smart, PhD, Professor in Exercise and Sports Science at Australia's University of New England.

He knows: he’s the author of a review of studies published in Sports Medicine that clarified that each type of exercise acted on cholesterol in slightly different ways.And overall, workouts are useful: Exercise lowered participants' LDL ("bad" cholesterol) by about 7 milligrams per deciliter (mg/dL), reduced artery-clogging very low-density lipoprotein (vLDL) by about 4 mg/dL, and took down triglycerides by about 8 mg/dL on average.

Working out increased HDL ("good" cholesterol) by about 2 mg/dl.Those might not seem like huge takedowns (or lifts, when it comes to HDL, which you want to be high). But here’s the thing: In addition to all of the aspects of cholesterol that exercise affects, it can do what drugs and diet can’t: It can raise HDL, he explains.

That’s important, because that’s the marker that usually needs extra help. Virtually everyone with high levels of harmful lipids has low HDL, says Smart. While low HDL is half the problem with their cholesterol, it's comparatively harder to fix with medications like statins.Here’s how each type of exercise can help improve your cholesterol:How Cardio Affects CholesterolCARDIO—AEROBIC ACTIVITIES like walking, running, swimming, and cycling—not only reduces total cholesterol, LDL, vLDL and triglycerides, it starts working on your blood fats right away.

These workouts burn triglycerides in your bloodstream as fuel.Then, over time, consistent training acts on both LDL and HDL. Here’s how it works:To Take Down Your LDLRegular aerobic activity alters LDL cholesterol so that it clears out of your blood more easily and causes less harm while it's there.

Specifically, cardio:• Helps break down fats in your blood by boosting enzymes (including one called lipoprotein lipase) that do that kind of work.• Gets LDL out before it turns nasty. Cardio turns up your cells' LDL receptors so you clear more LDL from your blood before it has time to oxidize and damage the lining of your blood vessels.

"Oxidized LDL cholesterol is the kind that's dangerous," says Sara K. Rosenkranz, PhD, a professor of kinesiology and nutrition sciences at the University of Nevada-Las Vegas.• Reshapes LDL particles so they’re less dangerous. If you have high LDL, the particles themselves are small and dense, making them more likely to settle into artery walls, explains George A.

Kelley, DA, FACSM, a Research Professor in the School of Public and Population Health at Boise State University. "Exercise seems to make them more puffy, less dense, and those have been shown to contribute less to atherosclerosis."To Raise Your HDLAerobic exercise can increase HDL by about 10 percent and improve its function, says William E.

Kraus, M.D., Professor of Medicine at Duke University. Cardio workouts:• Reduce HDL particle size. Exercise helps your body produce small HDL particles, which are especially good at removing cholesterol before it has time to form dangerous plaques in your blood vessels, says Kraus.• Improve HDL's ability to remove bad cholesterol from your blood.

Docs call this process cholesterol efflux. "At high intensities or in high amounts, exercise seems to increase our ability to efflux, so it makes your HDL function better," says Mark Sarzynski, Ph.D., an associate professor of exercise science at the University of South Carolina. In other words, exercise gets blood pumping through your blood vessels, which might stimulate more HDL to get to work, he says.

How Weight Training Affects CholesterolRESISTANCE TRAINING CAN raise HDL levels about as much as aerobic exercise does, and the two work better together, according to the Sports Medicine study review. Smart says a small number of studies also suggest that resistance training can improve LDL, vLDL, and triglycerides, but more data is needed.

Scientists are still working to explain how resistance training raises HDL. However, Smart has a theory. Consider that HDL is a protein-rich type of cholesterol. When you lift weights, you break down protein-rich muscle fibers and then repair them during rest. "It makes sense that HDL would respond better to a protein-building activity like resistance training," says.

Research also suggests that lifting at low or moderate intensities (about 50 to 75 percent of your one-rep max) might improve HDL levels by increasing the activity of enzymes that help HDL shuttle artery-clogging lipids to your liver for disposal.How Much Do You Need to Work Out to Change Your Cholesterol?

TO CHANGE YOUR cholesterol, you need to burn about 1,000 to 1,200 calories during exercise (or about 11.25 Metabolic Equivalent Hours or MET Hours) per week, says Smart. There are many ways to get there; you can do longer sessions at a lower intensity or shorter ones at a higher intensity.Say, for example, you weigh 180 pounds and like walking as your cardio.

Take five weekly 50-minute walks at a pace of 2.5 miles per hour to hit your goal. If you move more slowly, walk longer. If you pick up the pace, you can cut the time.Note that more time does seem to equal extra benefits. Smart's research showed that adding just a minute to each workout session could raise HDL by 2 mg/dL over an average of 12 weeks.

Adding more sessions helps, too: Each extra weekly cardio workout reduced triglycerides by about 8 mg/dL. There's probably a plateau at some point, but we don't know how many weeks it will take, says Smart. Most studies lasted about 12 weeks, with a range of 3 to 52 weeks.For resistance training to help with cholesterol, lift two to three times per week.

Do one to three sets of eight to 10 exercises at about 40 to 80 percent of your one-rep max for the big muscle groups: arms, legs, chest, and back, suggests Kelley. Rest for two to three minutes between each exercise and between each set.The more you exercise, the more results you'll see. If you're consistent, you might improve your lipid numbers in four to eight weeks, says Kelley.

Exercise Is Important—And So Is Food"EXERCISE'S EFFECT ON LDL cholesterol is relatively small as compared to some of our other established treatments, medications, and diet changes, but it's still meaningful," says Dr. Rosenkranz. Regular aerobic activity can drop your LDL by 5 to 10 percent, she adds.

Cardio and weights raise HDL about the same amount.Of course, when you’re looking to change your cholesterol, you can’t stop there. The old rule still applies: You can't outrun a bad diet."Even if you're exercising an hour a day, there are still 23 hours of the day that really matter for metabolizing things, including fats and lipids," says Sarzynski.

Combining exercise and diet changes can help you reduce your LDL by 20 to 30 percent, says Rosenkranz. If you eat better and move more, you might lose body fat, which can also slash high cholesterol levels.Exercise and diet also improve insulin sensitivity and chronic inflammation, reducing your risk of arterial damage from elevated cholesterol, says Kelley.

Of course, cholesterol isn't the only endpoint in terms of how cardio and weights help your cardiovascular health. "Exercise is going to improve a lot of other things as well, such as blood pressure, blood glucose control, body weight, and body composition," says Smart. That adds up to a reduction in your overall risk of heart disease, and that’s the whole point.

If you have genetically high cholesterol, lifestyle changes alone might not lower your numbers enough to avoid lipid-lowering medication such as statins. However, they might help you start with a lower dose, says Rosenkranz.Julie Stewart is a writer, editor and content strategist with over a decade of experience translating complex topics — health and medicine, science and engineering — into engaging, accessible stories.

Her work has appeared in publications like Men’s Health, Women’s Health, AARP The Magazine, EatingWell and Prevention, and she has also led strategic communications for a top engineering college and a global oncology company.

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